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目的:探索694 nm点阵红宝石激光联合左旋维生素C超声导入治疗黄褐斑的疗和安全性。方法:黄褐斑患者26例。每位患者签署同意书后,利用694 nm点阵红宝石激光对患者的面部色斑部分进行均匀扫描,能量密度为2.5~4 J/cm~2,频率为1.5 Hz,脉冲时间为10ns,光斑大小为7.1×7.1 mm。激光治疗后立即进行左旋维生素C的超声波导入,频率为1 MHz,能量为0.5 W/cm~2。每次治疗间隔2周,共进行4~6次治疗。两位独立的调查员在每次治疗后进行回访,调查黄褐斑的皮损面积及严重程
Objective: To explore the treatment and safety of melasma with 694 nm lattice ruby laser combined with L-ascorbic acid. Methods: Chloasma patients in 26 cases. After each patient signed the consent form, the patient’s facial stains were scanned uniformly by 694 nm ruby laser. The energy density was 2.5-4 J / cm ~ 2, the frequency was 1.5 Hz, the pulse time was 10 ns, the spot size was 7.1 × 7.1 mm. L-ascorbic acid was introduced immediately after laser treatment at a frequency of 1 MHz with an energy of 0.5 W / cm2. Each treatment interval of 2 weeks, a total of 4 to 6 treatments. Two independent investigators conducted a follow-up visit after each treatment to investigate the area and severity of melasma lesions