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目的探讨大型未破裂颅内动脉瘤的血流动力学特点。方法结合数字减影血管造影(DSA)三维图像,采用计算流体力学(CFD)有限元方法的软件,对12例直径≥15 mm的未破裂颅内动脉瘤进行数值模拟,对其血流动力学参数进行分析,并与其载瘤动脉上的参数相对比。结果大型动脉瘤内部涡流形态复杂,在主要涡流内部有大面积紊乱的低速流动。动脉瘤瘤颈处速度最大,瘤顶附近存在一个面积较大的低流速区,流速接近0;与其载瘤动脉相比,收缩期末平均壁面切应力(WSS)显著降低,平均切应力震荡因子(OSI)显著增高,瘤壁平均低WSS面积百分比为24.74%。结论未破裂大型动脉瘤的血流动力学特点为紊乱的涡流、瘤顶附近较大面积的低流速区、瘤壁高OSI和大面积的低WSS区。
Objective To investigate the hemodynamic characteristics of large unruptured intracranial aneurysms. Methods Combined with three-dimensional digital subtraction angiography (DSA) images, 12 cases of non-ruptured intracranial aneurysms with a diameter of ≥15 mm were numerically simulated with CFD finite element method. The hemodynamics The parameters were analyzed and compared with those on the parental artery. Results The internal eddy current of large aneurysm was complex and had a large area of disorder and low velocity flow in the main eddy. Aneurysm neck at the maximum velocity, there is a tumor area near the top of a large area of low flow velocity close to 0; compared with its parent artery, the average wall shear stress at the end of systole (WSS) decreased significantly, the average shear stress shock factor OSI) was significantly higher, the average wall area of low WSS percentage was 24.74%. Conclusions The hemodynamic characteristics of unruptured large aneurysms are turbulent turbulence, large areas of low flow velocity near the tumor dome, high OSI and large area of low WSS.