A comprehensive analysis was conducted on the current situation as well as historic succession process of agriculture and ecological conditions in Northwest China, in particular in the Loess Plateau, by means of a inter-disciplinary approach of ecology, agro-geohistory, and agronomy. It was concluded that the fundamental causes responsible for the ecological deterioration, signed by the poor agro-productivity and serious soil erosion, had been the extensive cropping system by ever-increasing reclamation on semi-drought slope land, where initiated a natural vegetation of brushy grasses with sparse trees, thus suitable only for A comprehensive analysis was conducted on the current situation as well as historic succession process of agriculture and ecological conditions in Northwest China, in particular in the Loess Plateau, by means of a inter-disciplinary approach of ecology, agro-geohistory, and agronomy. It was concluded that the fundamental causes responsible for the ecological deterioration, signed by the poor agro-productivity and serious soil erosion, had been the extensive cropping system by ever-increasing reclamation on semi-drought slope land, where initiated a natural vegetation of brushy grasses with sparse trees, thus suitable only for