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目的:对比干预前后我院外科3种Ⅰ类切口手术围术期预防性应用抗菌药的合理性,考察干预措施的实施效果。方法:选取2009年1～12月(干预前)及2010年1～12月(干预后)3种Ⅰ类切口手术的出院病历,对比干预前、后预防性应用抗菌药的合理性。结果:干预后术前0.5～2 h内给药率86.9%,一代头孢菌素的使用率为77.6%,抗菌药用药时机和药物选择的合理性提高,但仍存在应用率高、用药时间长等问题。结论:医院采取的干预措施具有可行性和有效性,对促进安全、有效、经济、合理地使用抗菌药起到了积极作用。
OBJECTIVE: To compare the rationality of prophylactic use of antibacterials during the perioperative management of three kinds of incisions in our hospital before and after the intervention, and to investigate the effect of the interventions. Methods: The discharge records of three kinds of incision Ⅰ incisions from January to December 2009 (before intervention) and from January to December 2010 (after intervention) were selected to compare the rationality of prophylactic use of antibacterials before and after intervention. Results: The rate of application of cephalosporin in first generation was 86.9% within 0.5-2 h after the intervention, and the rate of first generation cephalosporin was 77.6%. The rationality of timing and selection of antibacterial drugs was improved. However, there were still some problems such as high application rate and long medication time And other issues. Conclusion: The interventions taken by the hospital are feasible and effective and play an active role in promoting the safe, effective, economical and rational use of antibacterial drugs.