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目的 探讨幕上脑胶质瘤与脑内室管膜瘤的CT、MRI表现与病理肿瘤间质特性的相关性 ,为诊断治疗提供依据。方法 进行胶质瘤 (6 0例 )和室管膜瘤 (40例 )的CT和MRI配合MRPWI、MRS、MRA表现与手术病理(光镜和电镜 )超微结构和免疫组化对照研究。结果 胶质瘤和脑内室管膜瘤的CT和MRI显示的肿瘤形态不规则、分叶状、瘤壁及瘤结节、坏死囊变区、出血、瘤血管等表现 ,与手术病理肿瘤超微结构与肿瘤标记物表达相符合。结论 对胶质瘤和脑内室管膜瘤的间质生物学特性的CT、MRI研究 ,可提高预测肿瘤的病理分级的准确性 ,对临床实施抗肿瘤血管生成等多种方法配合手术治疗 ,对根治或控制肿瘤生长有帮助。
Objective To investigate the correlation between CT and MRI features of supratentorial gliomas and intracerebral ependymoma and pathological features of tumor stroma and to provide evidence for diagnosis and treatment. Methods CT and MRI of glioma (60 cases) and ependymoma (40 cases) were studied with MRPWI, MRS, MRA and pathology (light and electron microscopy) ultrastructure and immunohistochemistry. Results CT and MRI of glioma and ependymoma showed irregular shape, lobulated, tumor wall and tumor nodules, necrotic area, hemorrhage, tumor blood vessels and other performance, and surgical pathology Microstructures corresponded to tumor marker expression. Conclusions The CT and MRI studies of interstitial biological characteristics of glioma and ependymoma can improve the accuracy of the prediction of the pathological grade of the tumor and provide a variety of methods such as anti-angiogenesis in clinical practice with surgical treatment, It is helpful to cure or control tumor growth.