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本文收集胃癌手术切除标本189例,胃溃疡标本44例。各取癌旁或溃疡旁组织4块,石蜡切片,作HE与粘液组化染色,对比观察癌旁、溃疡旁粘膜小肠与结肠型肠化、肠型与胃型不典型增生,及其与胃癌组织学分型的关系。结果表明:癌旁粘膜中,重度不典型上皮增生是胃癌的重要癌前病变;肠型不典型增生与管状腺癌关系十分密切。复习有关文献,对胃癌的组织发生问题作了讨论。
This article collected 189 cases of surgical resection of gastric cancer, 44 cases of gastric ulcer specimens. Paraffin-embedded or para-cancer tissue 4 pieces and paraffin sections were used for HE and mucin histochemical staining. Contrast paratumoral and para-mucosal mucosal intestinal and colonic intestinal metaplasia, intestinal type and gastric dysplasia, and gastric carcinoma were compared. The relationship between organizational types. The results showed that severe atypical epithelial hyperplasia was an important precancerous lesion of gastric cancer in the paraneoplastic mucosa; intestinal dysplasia was closely related to tubular adenocarcinoma. Review the relevant literature to discuss the occurrence of gastric cancer.