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从1995年9月至1996年2月,作者医院对卡孕栓和米索前列醇配伍米非司酮,用于终止早孕的药物进行了对照性研究。卡孕栓组(简称卡组)50例,米索前列醇组(简称米组)49例。两组病例在年龄、停经日数和米非司酮用量上经检验无差异。用药结果:卡组胚胎排出成功率90.0%,排出时间3.54±1.50小时;米组成功率83.7%,排出时间2.93±1.42小时,二者经检验无显著差异。但此两种药物均有不同程度的副作用,主要表现为:出血多、消化道症状和一过性休克。我们的研究结果表明:①卡孕栓和米索前列醇都是配伍米非司酮的有效流产药物,且二者的疗效及副作用无显著差异,②卡孕栓流产的成功率略高于米索,出血少,但用药较不便;③米索前列醇用药简便,流产时间稍短于卡孕栓,但出血较多,个别病例可以有一过性休克,应当警惕。
From September 1995 to February 1996, the authors performed a controlled study of carbamazepine and misoprostol in combination with mifepristone, a drug used to terminate early pregnancy. Cardiopulmonary intervention group (card group) 50 cases, misoprostol group (referred to as group) 49 cases. Two groups of patients in the age, menopause days and the amount of mifepristone on the test no difference. The results of medication: card group embryo discharge success rate of 90.0%, discharge time of 3.54 ± 1.50 hours; rice group success rate of 83.7%, discharge time of 2.93 ± 1.42 hours, both tested insignificant difference. However, these two drugs have different degrees of side effects, mainly as follows: bleeding, gastrointestinal symptoms and transient shock. Our results show that: ① card pregnant suppository and misoprostol are compatible mifepristone effective abortion drugs, and the efficacy and side effects of the two no significant difference ② the success rate of caesarean miscarriage slightly higher than the meter Cable, less bleeding, but the medication is more inconvenient; ③ misoprostol medication is simple, abortion time slightly shorter than the card pregnant plug, but more bleeding, individual cases can have transient shock, should be vigilant.