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应用氨力农治疗３５例严重充血性心力衰竭（ＣＨＦ），治疗前后测定左室舒张功能及血浆中肾素活性（ＰＲＡ）、血管紧张素Ⅱ（ＡⅡ）和醛固酮（ＡＬＤ）浓度。结果显示，氨力农可明显改善ＣＨＦ患者的左室舒张功能及降低血浆中ＡⅡ和ＡＬＤ浓度。其作用机理可能在一定程度上与神经体液因素有关。
35 cases of severe congestive heart failure (CHF) were treated with amrinone. Left ventricular diastolic function and plasma renin activity (PRA), angiotensin Ⅱ (AⅡ) and aldosterone (ALD) concentrations were measured before and after treatment. The results showed that amrinone can significantly improve left ventricular diastolic function in CHF patients and reduce plasma concentrations of AII and ALD. Its mechanism of action may be related to neurohumoral factors to some extent.