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为探讨乙型肝炎表面抗原（ｈｅｐａｔｉｔｉｓ Ｂ ｓｕｒｆａｃｅ ａｎｔｉｇｅｎ， ＨＢｓＡｇ）阳性母亲的婴儿乙肝疫苗注入后早期机体免疫反应的特点，采用化学发光法测定了吞噬细胞的吞噬功能；用双抗原夹心法测定了抗－ＨＢｓ抗体。结果表明，（１）乙肝疫苗注入前两组间吞噬细胞的吞噬功能无明显差异，疫苗注入后３个月和６个月时实验组外周血吞噬细胞的吞噬功能明显下降（Ｐ＜０．０５）。两组间同时间点相比，１个月和３个月都有显著性差异（Ｐ＜０．０１，Ｐ＜０．０５）。（２）乙肝疫苗注入后各时间点抗－ＨＢｓ阳转率两组间无明显差异。可见 ＨＢｓＡｇ阳性母亲的婴儿接受乙肝疫苗注入后，早期机体免疫反应的变化与健康母亲的婴儿确有不同，两者外周血吞噬细胞吞噬功能的变化表现不同的规律。
In order to investigate the characteristics of early post-injection of hepatitis B vaccine in infants infected with hepatitis B surface antigen (HBsAg) -positive mothers, the phagocytic function of phagocytes was determined by chemiluminescence method. -HBs antibody. The results showed that (1) there was no significant difference in the phagocytic function of the phagocytes between the two groups before the hepatitis B vaccine was injected. The phagocytic function of phagocytes in the peripheral blood of the experimental group decreased significantly at 3 and 6 months after vaccination (P <0.05 ). There was a significant difference between the two groups at the same time point (P <0.01, P <0.05) at 1 month and 3 months. (2) There was no significant difference between the two groups in anti-HBs positive rate at each time point after hepatitis B vaccine injection. Can be seen HBsAg-positive mothers infants receiving hepatitis B vaccine infusion, early changes in the immune response and healthy mothers do have different infants, both peripheral blood phagocytic phagocytic function of the performance of different laws.