论文部分内容阅读
采用PCR和breath by breath方法,对上海汉族55名优秀游泳运动员、60名优秀赛艇运动员和85名汉族普通人的ACE基因I/D多态性和V。O2max进行检测。结果显示1)上海汉族优秀游泳和赛艇运动员ACE基因的基因型和等位基因频率与上海和成都地区汉族普通人组无明显差异(P>0.05);与Caucasian人群相比,均存在非常显著性差异(P<0.0001),表现出明显的民族和地区的差异性;游泳和赛艇项目健将和一级运动员间的基因型和等位基因频率分布,存在明显差异(P<0.05);游泳运动员水平越高,II型所占比例就越高,赛艇运动员中水平越高,ID型的比例越大;2)不同基因型的游泳运动员的O2max、O2max/kg、CO2max、Emax、O2-plusemax、Wmax和Tmax等指标,均表现为II型>DD型>ID型,II型明显优于ID型(P<0.05~0.01),而赛艇运动员则表现为ID型>II型>DD型,ID明显优于DD型(P<0.05~0.01)。结果提示,游泳项目中具有II基因型或I等位基因的运动员,赛艇项目中具有ID基因型或I等位基因的运动员,可能属于运动训练敏感的高反应群体,经过多年系统科学的训练,具有成为优秀运动员的可能。ACE基因I/D多态性可作为运动训练和选材中高敏感的、非常重要的遗传标记之一。
The PCR and breath by breath method were used to detect ACE gene I / D polymorphism in 55 Han nationality elite swimmers, 60 elite rowers and 85 Han normals. O2max for testing. The results showed that 1) There was no significant difference in the genotype and allele frequencies of ACE gene among Shanghai Han nationality elite swimmers and rowers compared with the Han general population in Shanghai and Chengdu (P> 0.05) (P <0.0001), which showed obvious national and regional differences. There were significant differences in genotype and allele frequency distribution between swimmers and rowers athletes and first-class athletes (P <0.05); swimming The higher the level of athletes, the higher the proportion of type II, the higher the level of rowers, the greater the proportion of ID type; 2) O2max, O2max / kg, CO2max, of swimmers of different genotypes Emax, O2-plusemax, Wmax and Tmax all showed type II> type DD> type ID, type II was significantly better than type ID (P <0.05-0.01), while rowing athletes showed type II> II Type> DD, ID was significantly better than DD (P <0.05 ~ 0.01). The results suggest that athletes with II genotype or I allele in the swimming program and athletes with ID genotype or I allele in the rowing program may belong to the highly responsive group with exercise training sensitivity and after many years of systematic and scientific training , With the possibility of becoming a good athlete. ACE gene I / D polymorphism can be used as one of the most sensitive and important genetic markers in exercise training and material selection.