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目的研究1例人感染高致病性禽流感(H5N1)病例,为今后开展人禽流感防控工作提供科学依据。方法根据流行病学调查、临床表现、血清学检查、病毒分离及RT-PCR、Read-PCR法进行分析和诊断。结果此例患者为人感染高致病性禽流感(H5N1)实验室确诊病例,经抢救治疗无效因呼吸循环衰竭死亡。患者有明确病死禽接触史、典型临床症状与体征和实验室病原学依据。经采用隔离治疗、个人防护、医学观察、家禽捕杀和消毒等措施,疫情得到控制。结论加强禽流感疫情监测,禁止宰杀、食用病死家禽,采取综合性防控措施,是预防疫情发生的关键。
Objective To study a case of human infection with highly pathogenic avian influenza (H5N1) and provide a scientific basis for prevention and control of human bird flu in the future. Methods According to epidemiological investigation, clinical manifestations, serological tests, virus isolation and RT-PCR, Read-PCR method for analysis and diagnosis. Results The patient was diagnosed as H5N1 in laboratory and died of respiratory failure after rescue treatment failed. Patients have a clear history of poultry deaths, typical clinical signs and symptoms and laboratory etiology. The epidemic was under control after isolation treatment, personal protection, medical observation, poultry hunting and disinfection, etc. were adopted. Conclusion Strengthening the surveillance of bird flu, prohibiting slaughtering, eating dead poultry and adopting comprehensive prevention and control measures are the keys to prevent the outbreak.