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[目的]了解重症监护病房(ICU)医院感染中革兰阳性(G+)菌流行病学分布及对抗菌药物的耐药性。[方法]对2008年1～12月本院ICU分离的G+菌及其耐药性进行回顾性分析。[结果]共分离出G+菌126株,其中高达47.6%来源于呼吸道,其次是血液占31.7%。G+菌感染以耐甲氧西林金黄色葡萄球菌(MRSA)为主(42.9%),耐甲氧西林表皮葡萄球菌(MRSE)占15.8%。G+菌对利奈唑胺和万古霉素最敏感。[结论]ICU医院感染中G+菌以耐甲氧西林葡萄球菌为主,G+菌对万古霉素和利奈唑胺的敏感率最高。加强医院感染G+菌流行病学调查及耐药性分析,对控制医院感染十分重要。
[Objective] To understand the epidemiological distribution of Gram-positive (G +) bacteria in intensive care unit (ICU) nosocomial infections and its resistance to antibacterials. [Method] Retrospective analysis was performed on the G + bacteria isolated from ICU in our hospital from January to December in 2008 and its drug resistance. [Result] A total of 126 strains of G + bacteria were isolated, of which up to 47.6% originated from respiratory tract, followed by 31.7% from blood. The infection with G + was mainly methicillin-resistant Staphylococcus aureus (MRSA) (42.9%) and methicillin-resistant Staphylococcus epidermidis (MRSE) was 15.8%. G + bacteria are the most sensitive to linezolid and vancomycin. [Conclusion] Staphylococcus aureus is the main cause of G + infection in ICU nosocomial infection, and G + is the most sensitive to vancomycin and linezolid. To strengthen the epidemiological investigation of hospital infection G + and drug resistance analysis, is very important for the control of hospital infection.