当中枢神经和脑膜发生感染、外伤或肿瘤时,可引起脑脊液(CSF)性质、成分和量的改变。脑脊液实验室检查对中枢神经系统疾患的性质、签别诊断、疗效及预后观察都有十分重要的意义。本文仅就近年来脑脊液的临床医学检验的某些进展略述如下。蛋白质正常脑脊液中的蛋白总量为20-45mg%。小儿稍高于此值。约80%为白蛋白、20%为球蛋白。过去测定脑脊液蛋白质大多数采用传统的半定量法如Esbach法、米吉氏法、潘迪氏法。对于脑脊液蛋白定量测定普 Infection, trauma or cancer of the central nervous and meninges can cause changes in the nature, composition, and amount of cerebrospinal fluid (CSF). Cerebrospinal fluid laboratory tests on the nature of the central nervous system disorders, diagnosis of the sign, efficacy and prognosis of the observation is of great significance. This article only summarizes some of the advances in clinical medicine of cerebrospinal fluid in recent years. The total protein in normal cerebrospinal fluid is 20-45 mg%. Children slightly higher than this value. About 80% of albumin, 20% of globulin. Most of the past determination of cerebrospinal fluid protein using the traditional semi-quantitative methods such as Esbach method, Mickey’s method, Pandey’s method. Quantitative determination of CSF protein