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黑棘皮病是一少见的皮肤病,表现为明显的色素沉着与绒毛样或湿疣状损害,口腔粘膜也可有同样表现。由于黑棘皮病可能是内脏恶性肿瘤的皮肤与/或口腔的表现,所以临床上必须提高对潜在危险性的警惕。根据国内1952年
Acanthosis nigricans is an uncommon skin disease manifested by marked pigmentation and villous or wet callus-like lesions. The oral mucosa may also have the same appearance. Since acanthosis can be a manifestation of the skin and/or the oral cavity of visceral malignancies, clinical attention must be paid to the potential risk. According to domestic 1952