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目的 探讨肾移植术后巨细胞病毒感染的临床特点及治疗措施。方法 对24 例肾移植术后感染巨细胞病毒的患者的临床资料、血液生化指标、病前免疫抑制剂的应用及治疗进行分析。结果 发病于术后1 ～2 个月2 例,2 ～3个月16 例,3 ～4 个月5 例,术后14 个月1 例。24 例中3 例无症状,21 例以巨细胞病毒肺炎形式发病。治愈16 例,死亡8例,病死率占33 .33 % ,比文献报道低。结论 肾移植术后巨细胞病毒感染发病与免疫抑制剂的应用和种类有关,多以巨细胞病毒肺炎形式发病。治疗主张早期预防,适当调节免疫抑制剂,并配合支持疗法
Objective To investigate the clinical features and treatment of cytomegalovirus infection after renal transplantation. Methods The clinical data of 24 patients with cytomegalovirus infection after renal transplantation, blood biochemical parameters, the application and treatment of pre-immune immunosuppressants were analyzed. Results The incidence of 1 to 2 months after surgery in 2 cases, 2 to 3 months in 16 cases, 3 to 4 months in 5 cases, 14 months after surgery in 1 case. Of the 24 patients, 3 were asymptomatic and 21 were infected with cytomegalovirus pneumonia. 16 cases were cured and 8 died, the fatality rate was 33.33%, lower than that reported in the literature. Conclusion The incidence of cytomegalovirus infection after kidney transplantation and the application of immunosuppressive agents are related to the types, mostly in the form of cytomegalovirus pneumonia. Treatment advocates early prevention, appropriate modulation of immunosuppressive agents, and with supportive therapy