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许多报导指出,在工业生产上接触苯,增加患白血病的危险,但动物实验尚没有得到证实。C_(57)BL/6 N小鼠对放射性或化学物质诱发白血病相当敏感,因而用作苯诱发白血病试验。本文作者使用断奶的雄性C_(57)BL/6 N小鼠,分成三组:(1)80只小鼠皮下注射溶于玉米油的30%的苯,每周两次,共44周,以后每周一次,直至54周。前四周注射剂量分别为0.05,0.1,0.1和0.2毫升,以后每次注射0.2毫升;(2)20只小鼠皮下注射玉米油,注射时间
Many reports indicate that exposure to benzene in industrial production increases the risk of leukemia, but animal experiments have not yet been confirmed. C_ (57) BL / 6 N mice are quite sensitive to radioactive or chemical-induced leukemia and are therefore used as benzene-induced leukemia test. The authors used weaned male C57BL / 6N mice divided into three groups: (1) 80 mice were injected subcutaneously with 30% benzene in corn oil twice a week for 44 weeks Once a week until 54 weeks. The first four weeks the injection dose were 0.05,0.1,0.1 and 0.2 ml, after each injection of 0.2 ml; (2) 20 mice subcutaneously injected with corn oil, injection time