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目的:观察留置布地奈德混悬液明胶海棉对鼻内镜手术后中鼻道术腔上皮化的影响。方法:慢性鼻窦炎、鼻息肉患者48例随机分为治疗组与对照组,均给予鼻内镜鼻窦手术及常规术后处理。治疗组鼻内镜清理检查后于中鼻道术腔内留置浸有布地奈德混悬液的明胶海棉,1次/周,共3~6周,对照组仅行常规清理。结果:治疗组术腔黏膜上皮化时间明显短于对照组(P<0.01)。结论:慢性鼻窦炎鼻息肉鼻内镜术后术腔局部应用糖皮质激素可取得较好临床疗效。
Objective: To observe the effect of budesonide suspension gelatin sponge on the epithelization of middle ear canal after endoscopic sinus surgery. Methods: 48 patients with chronic sinusitis and nasal polyps were randomly divided into treatment group and control group. All cases were given endoscopic sinus surgery and conventional postoperative management. After treatment of nasal endoscopy in the treatment group, gelatin sponge soaked in budesonide suspension was placed in the middle-nasal cavity, once / week for 3 to 6 weeks. The control group was only routinely cleaned. Results: The mucosal epithelization in the treatment group was significantly shorter than that in the control group (P <0.01). Conclusion: Local application of glucocorticoid in patients with chronic sinusitis and nasal polyps after endoscopic sinus surgery can achieve better clinical curative effect.