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目的了解尿毒症患者的红细胞免疫功能的改变及血液透析的影响．方法：按Ｓｉｅｇｅｌ建立的标准红细胞免疫粘附试验（ＲＣＩＡ）进行。结果：尿毒症组 ＲＢＣ—Ｃ３ｂＲＲ水平低于正常对照组（ｐ＜ ０．０１）． ＲＢＣ－ＩＣＲ水平高于正常对照组（Ｐ＜０．００１）。血液透析组ＲＢＣ—ＩＣＲ水平低于内科一般治疗组（Ｐ＜０．０５）。结论：尿毒症患者存在继发性红细胞免疫功能低下，系外周血循环免疫复合物（ＣＩＣ）升高所致。血液透析可提高红细胞免疫功能．清除血循环中的部分ＩＣ．但不能改变巳低下的红细胞免疫粘附功能。故促进红细胞免疫功能的药物仍需要进一步探讨。
Objective To understand the changes of erythrocyte immune function and hemodialysis in patients with uremia. Methods: The standard erythrocyte immunoadhesion test (RCIA) established by Siegel was performed. Results: The level of RBC-C3bRR in uremia group was lower than that in normal control group (p <0.01). RBC-ICR levels were higher than the normal control group (P <0.001). RBC-ICR levels in hemodialysis group were lower than those in general medical treatment group (P <0.05). Conclusion: Uremia patients have secondary erythrocyte immune dysfunction, the Department of peripheral blood circulating immune complexes (CIC) increased. Hemodialysis can improve red blood cell immune function. Remove part of the blood circulation IC. But can not change the already low erythrocyte immune adhesion function. Therefore, the promotion of red blood cell immune function of the drug still need further study.