近年来证明,肺不仅是一个呼吸器官,且具有重要的内分泌功能。肺组织内的一些内分泌细胞可产生、分泌、代谢多种激素。降钙素(Calcitonin,CT)为32个氨基酸组成的单链多肽。主要产生、贮存于甲状腺滤泡旁细胞(C细胞)内。近年发现,肺内亦可产生和分泌大量降钙素,其与肺部多种疾病有关,但对其生理病理意义目前尚不十分了解。 It has been demonstrated in recent years that the lung is not only a respiratory organ but also has an important endocrine function. Some endocrine cells in the lung tissue produce, secrete, and metabolize a variety of hormones. Calcitonin (CT) is a 32-amino acid single-chain polypeptide. It is mainly produced and stored in parathyroid follicular cells (C cells). In recent years, it has been found that a large amount of calcitonin can also be produced and secreted in the lung, which is related to various diseases in the lung, but its physiological and pathological significance is not yet fully understood.