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目的探讨肝硬化合并肝性脑病(HE)预后的影响因素。方法对86例肝硬化合并HE的临床资料进行回顾性分析,根据患者预后分为死亡组与存活组,比较两组病例诱因、重要生化指标(TBIL、ALB、Cr、PT)、Child-Pugh分级、HE分期、并发症。结果两组在上述观察指标间差异均有显著性意义(P<0.05,P<0.01)。结论诱因、肝肾功能、凝血功能、Child-Pugh分级、HE分期及并发症均影响肝硬化合并HE患者的转归,可作为评价此病预后的重要指标。
Objective To investigate the influencing factors of prognosis of cirrhosis combined with hepatic encephalopathy (HE). Methods The clinical data of 86 patients with liver cirrhosis complicated with HE were retrospectively analyzed. According to the prognosis of patients, the patients were divided into the death group and the survival group. The causes of the two groups were compared. The important biochemical indexes (TBIL, ALB, Cr, PT) HE staging, complications Results There was significant difference between the above two indexes in the two groups (P <0.05, P <0.01). Conclusion Inducement, liver and kidney function, coagulation function, Child-Pugh grading, HE staging and complications all affect the outcome of patients with cirrhosis complicated with HE and may be used as an important index to evaluate the prognosis of this disease.