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目的丙泊酚复合麻醉应用于实验猪心导管术效果的观察。方法实验猪,2～3月龄,体重15～25kg,雌雄不限,148头350例次。术前30min肌注硫酸阿托品0.3mg,盐酸吗啡5mg,肌注咪达唑仑0.2mg/kg,10min后进入浅睡眠。按2.5～3.5mg/kg体重,缓慢静注丙泊酚,很快进入麻醉状态,气管插管,进行心脏导管术。结果丙泊酚复合麻醉,诱导时间短,起效快,效果强,恢复快速平稳,而且无副作用。结论丙泊酚复合麻醉很适合猪心脏导管术的实验研究,是一种理想的麻醉方法。
Objective To observe the effect of propofol combined anesthesia on cardiac catheterization in experimental pigs. Methods Experimental pigs, 2 to 3 months of age, weighing 15 ~ 25kg, male and female is not limited, 148 head 350 times. 30min before intramuscular injection of atropine sulfate 0.3mg, morphine hydrochloride 5mg, intramuscular midazolam 0.2mg / kg, 10min after into light sleep. Press 2.5 ~ 3.5mg / kg body weight, intravenous infusion of propofol slowly into anesthesia, endotracheal intubation, cardiac catheterization. Results Propofol anesthesia, induction time is short, rapid onset, strong effect, rapid and stable recovery, and no side effects. Conclusion Propofol anesthesia is very suitable for pig heart catheterization experimental study, is an ideal method of anesthesia.