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目的探讨放射性125I粒子植入近距离放疗联合化疗治疗晚期肺癌的近期疗效。方法选取2011年8月至2012年12月在许昌市中心医院进行治疗的晚期肺癌的患者83例,随机分为对照组和治疗组,对照组采用紫杉醇和顺铂进行化疗治疗,治疗组在对照组的基础上采用125I粒子瘤内植入放射治疗,比较两组患者的临床效果。结果治疗组患者的总有效率明显高于对照组,两组相比具有显著性差异(P<0.05);治疗组患者的1年生存率和两年生存率明显高于对照组,两组相比具有统计学意义(P<0.05)。结论放射性125I粒子植入近距离放疗联合化疗治疗晚期肺癌具有互补作用,并且具有较好的近期疗效,患者的生存率也得到明显提高。
Objective To investigate the short-term effect of radioactive 125I seeds brachytherapy combined with chemotherapy in the treatment of advanced lung cancer. Methods Eighty-three patients with advanced lung cancer who were treated in Xuchang Central Hospital from August 2011 to December 2012 were randomly divided into control group and treatment group. Patients in control group were treated with paclitaxel and cisplatin, Group based on the use of 125I tumor implantation tumor radiotherapy, the clinical effects of two groups were compared. Results The total effective rate in the treatment group was significantly higher than that in the control group, with significant difference between the two groups (P <0.05). The 1-year survival rate and 2-year survival rate in the treatment group were significantly higher than those in the control group The ratio was statistically significant (P <0.05). Conclusion Radioactive 125I seeds implantation brachytherapy combined with chemotherapy for the treatment of advanced lung cancer has a complementary effect, and has a good short-term efficacy, the patient’s survival rate has also been significantly improved.