目的　研究操纵电脑对视觉诱发电位 (visual evoked poten- tials,VEPs)及心理行为的影响。方法　将从未操作过电脑且无眼疾者作为对照组 ,有操作电脑史而无眼疾者作为监测组。对两组进行 VEPs监测。同时采用 WHO“神经行为核心测验组合法”进行心理行为测试。结果　儿童监测组和成人监测组与之相对应的对照组 ,VEPs潜伏期 (PL)及波幅 (AMP)比较显示 ,无论儿童或成人的 PL延长、AMP下降有显著性差异 ;不同性别比较显示 ,儿童组和成人组男性较女性 PL延长 ,儿童组男性 AMP下降程度高于女性 (成人组变化无差异 )。操作电脑年限比较 ,年限长较年限短 PL延长 ,但 AMP下降不显著。对成人监测组与对照组的情绪状态进行比较 ,发现紧张、愤怒、疲倦分值皆低于对照组 ,有统计学意义。结论　 VEPs检测可为恒定性视神经功能异常提供客观依据 ,恒定性长时间操纵电脑视力明显下降。提示有初级视皮层功能障碍 ,视神经受到一定程度损害。情绪状态的改变可能由于长时间操作电脑或是由视神经受损所致 ,有待进一步研究 Objective To study the effects of computer manipulation on visual evoked potentials (VEPs) and psychological behaviors. Methods Patients who had never operated the computer and had no eye diseases as the control group had computer history and no eye disease as the monitoring group. VEPs were monitored in both groups. At the same time using the WHO “behavioral core test combination” psychological behavior test. Results Compared with the control group, the latency and PL of VEPs in children monitoring group and adult monitoring group showed that there was a significant difference in the decrease of AMP regardless of PL or prolongation of children or adults. The gender differences showed that children Men and women in group and adult group prolonged more than those in female group, and male AMP in children group decreased more than female group (no difference in adult group). Comparing the years of operation of the computer, the longer the duration of short PL extended, but AMP decreased not significantly. The emotional state of the adult monitoring group and the control group were compared and found that scores of tension, anger and fatigue were lower than the control group, with statistical significance. Conclusion VEPs test can provide an objective basis for the constant optic nerve dysfunction, and the constant visual acuity decreased significantly in the long-term manipulation of the computer. Tip primary visual cortex dysfunction, optic nerve suffered a certain degree of damage. Emotional changes may be due to long-term operation of the computer or by the optic nerve damage caused by, for further study