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目的对本院的鲍曼不动杆菌血流感染者进行临床特征及耐药性分析,为临床有效治疗提供有利证据。方法 23例血流感染者共检测出74株鲍曼不动杆菌,通过纸片扩散法检测鲍曼不动杆菌耐药性。结果 23例鲍曼不动杆菌血流感染者中,心脑血管疾病11例,糖尿病12例。头孢曲松钠、头孢唑啉钠、头孢他啶耐药率最高,分别为39.19%、21.62%、21.62%,其次为阿奇霉素、克林霉素、氧氟沙星,耐药率分别为17.57%、13.51%、13.51%,耐药率分析最低的青霉素液为0。结论鲍曼不动杆菌的血流感染者中的耐药性分析已明确,对于药物的有效选择起到了重要的作用。
Objective To analyze the clinical features and drug resistance of Acinetobacter baumannii in our hospital and provide favorable evidence for clinical effective treatment. Methods Totally 74 strains of Acinetobacter baumannii were detected in 23 cases of bloodstream infection. The drug resistance of Acinetobacter baumannii was detected by disk diffusion method. Results Of the 23 cases of Acinetobacter baumannii infection, 11 were cardiovascular and cerebrovascular diseases and 12 were diabetes mellitus. Ceftriaxone sodium, cefazolin sodium and ceftazidime showed the highest rates of resistance (39.19%, 21.62% and 21.62%, respectively), followed by azithromycin, clindamycin and ofloxacin. The rates of resistance were 17.57% and 13.51 %, 13.51%, the lowest rate of penicillin resistance analysis was 0. Conclusion The analysis of drug resistance in Acinetobacter baumannii infection has been made clear and plays an important role in the effective selection of drugs.