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急性脑膜炎双球菌性疾病的病死率,在过去30年没有得到改善。作者回顾这些病例提示死亡与脑水肿有关系。在18个月间(1978~1979年)32例17岁以下住院儿童,6例死亡(17%)。诊断是根据脑脊液或血培养,或从瘀点直接涂片鉴定细菌证实的,每天静脉内给以大约25万u/kg的青霉素G,某些病例在开始时每天用100mg/kg的氯霉素,但在获得实验室确诊后即停用。所有病例均给予维持静脉补液,某些病例并
The mortality rate of acute meningococcal disease has not improved over the past 30 years. The authors review these cases suggest that death and brain edema. During the 18 months (1978-1979), 32 children under the age of 17 were hospitalized and 6 died (17%). The diagnosis was confirmed on the basis of cerebrospinal fluid or blood cultures, or by direct smear-identification of bacteria from petechial sites, giving approximately 250,000 u / kg of penicillin G intravenously daily and in some cases initially with 100 mg / kg of chloramphenicol , But disabled after getting a laboratory diagnosis. All cases were given maintenance intravenous rehydration, some cases and