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目的探讨机械通气联合吸入用布地奈德混悬液治疗重症哮喘的临床疗效。方法收集2013年6月至2014年6月在我院接受治疗的重症哮喘144例患者资料,根据不同治疗方案将患者分为两组,均行机械通气(有创)治疗,对照组(72例)患者同时给予甲泼尼龙和氨茶碱静脉滴注治疗,观察组(72例)患者在对照组治疗的基础上加用布地奈德混悬液雾化吸入治疗,比较两组患者治疗效果。结果观察组患者总有效率为91.7%,明显高于对照组的69.4%,差异有统计学意义(P<0.05);观察组患者的各项指标变化情况明显优于对照组,差异均有统计学意义(均P<0.05)。结论在重症哮喘患者的治疗中采用机械通气联合布地奈德治疗效果明显。
Objective To investigate the clinical efficacy of budesonide suspension combined with mechanical ventilation in the treatment of severe asthma. Methods The data of 144 patients with severe asthma who were treated in our hospital from June 2013 to June 2014 were collected. The patients were divided into two groups according to different treatment plans. All patients underwent mechanical ventilation (invasive) treatment. The control group (72 patients ) Patients were treated with intravenous infusion of methylprednisolone and aminophylline. Patients in the observation group (72 patients) were treated with inhaled budesonide injections on the basis of the control group, and the therapeutic effect was compared between the two groups. Results The total effective rate of the observation group was 91.7%, which was significantly higher than that of the control group (69.4%, P <0.05). The changes of the indexes in the observation group were obviously better than those in the control group Significance (both P <0.05). Conclusion The treatment of severe asthma in patients with mechanical ventilation combined with budesonide treatment effect is obvious.