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非扩散性早期喉乳头状瘤恶变是极端罕见的。英国报告了一例,德国报告了两例。英国最早报告的1例是23岁的患者。早期喉乳头状瘤是青少年喉部最常见的肿瘤,这种肿瘤通常是增殖性的,它与成人乳头状瘤相比是截然不同的,成人喉乳头状瘤通常是单一的。其恶变是罕见的,早期喉乳头状瘤恶变最常见的是以前接受过放射治疗的病人。Toso引用一例英文记载非扩散性早期喉乳头状瘤恶变的病例中报导,该患35岁,曾采用过喉局部切除和颈部根治手术。德国Kaiser报导1例12岁女孩早期喉乳头状瘤恶变,该患早期未曾接受过放射治疗,而这次应用5870拉德钻放疗获得成功。Justus等
Non-dilated early malignant papilloma of the larynx is extremely rare. Britain reported one case and Germany reported two cases. One of the first cases reported in the United Kingdom was a 23-year-old patient. Early laryngeal papilloma is the most common tumor in the juvenile throat. This tumor is usually proliferative. It is distinct from adult papilloma. Adult laryngeal papilloma is usually single. The malignant transformation is rare, and the most common malignancy of early laryngeal papilloma is the patient who had previously received radiation therapy. Toso cited a case in which a report of a non-dilated early-stage laryngeal papilloma was documented in English. The patient was 35 years old and had had partial laryngectomy and radical neck surgery. Kaiser of Germany reported on the early malignant transformation of a laryngeal papilloma in a 12-year-old girl who had not received radiotherapy in the early stages. This time, she was successfully treated with radiotherapy of the 5870 Ladder. Justus et al