问:急性呼吸道感染时,皮质类固醇类药物如何应用? 答:在急性呼吸道感染时,不提倡用皮质类固醇,因为它们能损害宿主的免疫反应能力,增加真菌和其它感染率。尽管它们可暂时缓解急性期的症状,却可掩盖恶化中的感染。问:青霉素的用量日渐增加,是否能减少产生β-内酰胺酶的细菌的耐药问题? 答:此酶(β-内酰胺酶)是某些细菌的诱导酶,因此,在治疗早期,如果细菌没有机会大量产生此酶 Q: How are corticosteroids used in acute respiratory infections? A: Corticosteroids are not recommended for acute respiratory infections because they impair the host’s immune response and increase fungal and other infections. Although they temporarily relieve the symptoms of the acute phase, they mask the worsening infection. Q: The increasing use of penicillin, can reduce the resistance of bacteria producing β-lactamase? A: This enzyme (β-lactamase) is induced by certain bacteria, therefore, in the early stages of treatment, if Bacteria do not have the chance to produce this enzyme in large quantities