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本文作者报道了1例丙型肝炎病毒(HCV)感染者并发重症肌无力(MG)的病例。患者10年前有肝功能中度异常,4年前,肝脏超声扫描提示该患者有肝硬化症。此次患者因双上睑下垂入院。实验室检测发现:抗HCV阳性,抗AchR阳性,抗横纹肌抗体阳性,HCV RNA阳性。同时,免疫组化在肝中查到HCV抗原,吡啶斯的明实验阳性。患者被确诊为HCV感染并发MG。1年后,该患者死于呼吸循环衰竭。
The authors report a case of hepatitis C virus (HCV) infection in patients with myasthenia gravis (MG). The patient had a moderate abnormal liver function 10 years ago. Four years ago, a liver ultrasound scan suggested that the patient had cirrhosis. The patient was hospitalized with double upper eyelid ptosis. Laboratory tests found that: anti-HCV positive, anti-AchR positive, anti-striated antibody positive, HCV RNA positive. At the same time, immunohistochemistry found in the liver HCV antigen, pyridostigmine positive test. Patients were diagnosed with HCV infection complicated with MG. One year later, the patient died of respiratory failure.