目的探讨研究胺碘酮治疗心力衰竭并发心律失常的效果及安全性。方法选取我院近期治疗的心衰合并心律失常患者98例,将患者按1:1的比例分成a、B两组,B组患者选用常规抗心衰和心律失常药物治疗,a组患者在常规药物治疗基础上选用胺碘酮治疗,对比两组治疗的临床效果和不良反应情况。结果两组患者经不同方法治疗后,采用胺碘酮治疗a组的临床效果为:显效45例、有效2例、无效2例、有效率为96%,明显优于B组的相关情况,P<0.05。a组有恶心1例,食欲减退1例,不良反应率为4%;B组有恶心3例、头晕3例、震颤2例、低血压1例,不良反应率为18.4%。a组不良反应情况明显好于B组,P<0.05。对两组的不良反应病例采取对应药物和调整用药方法治疗后,患者均病情好转。结论胺碘酮在心衰并发心律失常的疾病治疗中具有较好的临床效果和较高的安全性,值得临床广泛推广与应用。 Objective To study the efficacy and safety of amiodarone in the treatment of heart failure with arrhythmia. Methods A total of 98 patients with heart failure and arrhythmia treated in our hospital were divided into two groups according to a ratio of 1: 1. Patients in group B were treated with conventional anti-heart failure and arrhythmia drugs. Patients in group a Drug treatment based on the choice of amiodarone treatment, the two groups compared the clinical effects and adverse reactions. Results After the two groups of patients were treated by different methods, the clinical effect of amiodarone in treatment of a group was: 45 cases markedly effective, 2 effective and 2 ineffective, the effective rate was 96%, which was significantly better than that of group B, P <0.05. In group a, nausea was found in 1 case, loss of appetite in 1 case and adverse reaction rate was 4%. In group B, nausea occurred in 3 cases, dizziness in 3 cases, tremor in 2 cases and hypotension in 1 case. The adverse reaction rate was 18.4%. A group of adverse reactions was significantly better than the B group, P <0.05. On the two groups of adverse reactions to take the corresponding drugs and adjust the medication method, the patients were in better condition. Conclusions Amiodarone has a good clinical effect and high safety in the treatment of heart failure and arrhythmia, which deserves wide application and promotion in clinic.