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在各种致癌因素诱发癌基因激活和抑癌基因失活及其基因表达产物的异常是细胞癌变的重要因素[1,2]。鼻咽癌癌基因与Ha-ras基因具有同源顺序;而且在鼻咽癌的发病中既发现有癌基因Ha-ras的活化,还有抑癌基因P53的突变以及位于7q32-ter特定区域...
In a variety of oncogenic factors induced oncogene activation and tumor suppressor gene inactivation and abnormal gene expression products is an important factor in cell carcinogenesis [1,2]. Nasopharyngeal carcinoma oncogene and Ha-ras gene homologous sequence; and in the pathogenesis of nasopharyngeal carcinoma found both oncogene Ha-ras activation, as well as tumor suppressor gene P53 mutation and in the 7q32-ter specific area. ..