论文部分内容阅读
乳腺癌是常见病。血卟啉衍生物(HPD)光动力学治疗(PDT)能有效地破坏肿瘤。测定HPD对雌激素受体(ER)的影响,为临床治疗提供了必要的依据。本文研究了50只200克重的雌性Sprague-Dawley大鼠,通过胃插管给予20mg二甲苯蒽。35只大鼠发生自发性乳腺肿瘤。当肿瘤直径达到2cm时,在动物腹腔内用戊巴比妥麻醉,每个肿瘤切除50％。随机分为三组;A组注射HPD2
Breast cancer is a common disease. Hematoporphyrin derivative (HPD) photodynamic therapy (PDT) can effectively destroy tumors. Determining the effect of HPD on estrogen receptor (ER) provides the necessary basis for clinical treatment. Here, 50 female Sprague-Dawley rats weighing 200 grams were studied and 20 mg of xylylene terephthalate was administered via gastric cannulation. Spontaneous breast tumors occurred in 35 rats. When the tumor reached a diameter of 2 cm, the animals were anesthetized with pentobarbital in the abdominal cavity, and 50% of each tumor was resected. Randomly divided into three groups; group A injected HPD2