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现行的肌肉接种3针乙型肝炎疫苗可有效地诱生机体的保护性机体。但缺点是免疫程序时间长,费用昂贵。本文作者采用2针、低剂量皮内免疫法,取得了满意的效果。乙型肝炎疫苗为Merck药厂的产品,含20μg/ml抗原蛋白。采用标准胰岛素注射器进行皮内注射,以减少损失。将22~42岁健康成人分3组进行免疫接种。ID-1组,19人,平均年龄为26.9±4.5岁,于第0、1和4个月分别皮内注射0.1ml(2μg)疫苗;ID-2组,24人,平均年龄为26.6±4.1岁,第1次双臂皮内各注射0.2ml(4μ)疫苗,4个月后单臂皮内注射0.1ml(2μg),两
Inoculation of the current 3-dose hepatitis B vaccination muscle can effectively induce the body’s protective body. But the disadvantage is that the immunization process takes a long time and is expensive. The authors used 2-pin, low-dose intradermal immunization and achieved satisfactory results. Hepatitis B vaccine is a product of Merck Pharmaceuticals, containing 20 μg / ml of antigenic protein. Intradermal injection with standard insulin syringes to reduce losses. The 22 to 42-year-old healthy adults were divided into 3 groups for immunization. The ID-1 group, 19 individuals, with an average age of 26.9 ± 4.5 years, received intradermal injection of 0.1 ml (2 μg) vaccine on days 0, 1, and 4, ID-2, 24, with an average age of 26.6 ± 4.1 Years old, the first arm intradermal injection of 0.2ml (4μ) vaccine, arm 4 months after intradermal injection of 0.1ml (2μg), two