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目的:评价小功率钬激光前列腺剜除术用于良性前列腺增生(BPH)治疗中的临床价值。方法:选择2012年1月~2015年6月收治的BPH患者312例,将患者随机分为2组,观察组(n=156)为行小功率钬激光前列腺剜除术组,对照组(n=156)为行经尿道前列腺电切术组。比较2组手术时间、切除增生重量、术后血清Na~+、血Hb、并发症、导尿管置留时间、住院时间以及术后最大尿流率(Q_(max))、国际前列腺症状评分(IPSS)、生活质量评分(QOL)、血清前列腺特异性抗原(PSA)。结果:两组患者围手术期指标结果显示,观察组切除标本重、血清Na~+、Hb、术后冲洗时间、尿管置留时间、术后住院时间及并发症等与对照组相比较,差异有统计学意义(P<0.05);两组患者术后随访结果显示,观察组3、6及12个月的Q_(max)、IPSS、QOL及PSA与对照组相比较,差异均无统计学意义(P>0.05)。结论:小功率钬激光前列腺剜除术与经尿道前列腺电切术用于治疗BPH疗效相当,且具有并发症发生率低的优点,值得在临床上推广应用。
Objective: To evaluate the clinical value of low-power holmium laser prostatectomy in the treatment of benign prostatic hyperplasia (BPH). Methods: A total of 312 BPH patients were selected from January 2012 to June 2015. The patients were randomly divided into two groups. The observation group (n = 156) underwent low-power holmium laser prostatectomy and the control group (n = 156) for transurethral resection of the prostate group. The time of operation, the weight of the proliferative lesion, the postoperative serum Na +, blood Hb, complications, catheterization time, hospitalization time and postoperative maximal urinary flow rate (Qmax) were compared between the two groups. The International Prostate Symptom Score (IPSS), quality of life score (QOL) and serum prostate specific antigen (PSA). Results: The results of perioperative indexes in the two groups showed that compared with the control group, the weight of specimens removed, serum Na +, Hb, postoperative irrigation time, catheterization time, postoperative hospital stay and complications in observation group were significantly lower than those in control group The difference was statistically significant (P <0.05). The follow-up results of two groups showed no significant difference in Q max, IPSS, QOL and PSA between the observation group and the control group at 3, 6 and 12 months Significance (P> 0.05). Conclusion: The small-power holmium laser prostatectomy and transurethral resection of prostate resection for the treatment of BPH is quite effective, and has the advantage of low complication rate, which is worth popularizing in clinic.