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目的 考察替硝唑葡萄糖注射液与洛美沙星注射液配伍的稳定性。方法 采用双波长紫外分光光度法分别考察两种输液等体积配伍前后的含量变化。结果 在室温条件下 ,0～ 6h内 ,其外观、pH及含量均无明显变化。按相应工作曲线下所述方法测定相应的A值和△A值 ,计算得替硝唑的回收率为 99 6 % (RSD =0 88% ,n =5 )和 99 3% (RSD =0 96 % ,n =5 ) ;洛美沙星的回收率为 10 0 1% (RSD =0 85 % ,n =5 )和 10 1 8% (RSD =1 2 2 % ,n =5 )。结论 替硝唑葡萄糖注射液与洛美沙星注射液在 6h内可以配伍。
Objective To investigate the stability of tinidazole and glucose injection combined with lomefloxacin injection. Methods Two-wavelength ultraviolet spectrophotometry was used to investigate the content changes of two kinds of transfusion volumes before and after compatibility. Results At room temperature, within 0 ~ 6h, the appearance, pH and content showed no significant changes. The corresponding values of A and △ A were determined by the methods described in the corresponding working curves. The calculated recoveries for tinidazole were 99.6% (RSD = 0 88%, n = 5) and 99 3% (RSD = 0 96 %, n = 5). The recoveries of lomefloxacin were 1001% (RSD = 0 85%, n = 5) and 101.8% (RSD = 122%, n = 5). Conclusion tinidazole glucose injection and lomefloxacin injection can be compatible within 6h.