最近 ,意大利研究者通过阻断大鼠肠系膜上动脉和腹主动脉干 (45 min)复制动物模型 ,研究钙激活蛋白抑制剂 I在内脏动脉夹闭损伤过程中的作用。研究发现 ,再灌注 1h大鼠平均动脉压显著下降 ;蛋白印迹分析显示回肠组织 IκBα表达显著减少 ;免疫组织化学分析显示坏死回肠组织中 P Recently, Italian researchers investigated the role of calpadrine I in the process of visceral arterial occlusion injury by blocking animal models of rat superior mesenteric artery and abdominal aortic trunk (45 min). The study found that 1 h after reperfusion, mean arterial pressure was significantly decreased; Western blot analysis showed that ileum tissue IκBα expression was significantly reduced; immunohistochemical analysis showed that necrotic ileum tissue P