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目的了解2012年首次进入云南省某强制戒毒所的女性性工作者(FSW)感染人免疫缺陷病毒(HIV)和性传播疾病(STD)病原体的感染情况,为该人群艾滋病和STD的防治提供依据。方法采集静脉血检测HIV,采集阴道分泌物用荧光定量PCR的方法检测STD的主要病原体:沙眼衣原体(CT),解脲支原体(UU),淋球菌(NG),单纯疱疹病毒Ⅱ型(HSV-Ⅱ),乳头瘤病毒6,11(HPV 6,11),乳头瘤病毒高危型(HPV HR)。结果 143例被检者中,检出HIV感染6例,感染率为4.19%;STD病原体检测:CT16例(11.19%),UU 86例(60.14%),NG 4例(2.80%),HSV-Ⅱ型32例(22.38%),HPV 6,11 7例(4.89%),HPV HR 51例(35.66%),共检出STD病原体196例,仅6例未检出上述病原体。单一病原体感染66例(46.15%),混合病原体感染71例(49.65%)。结论在当地吸毒的女性性工作者中,HIV和STD的感染不容忽视,二者相互促进又相互影响,应针对这类人群加强健康教育,采取有效的干预措施,控制STD和HIV的传播流行。
Objective To understand the infection status of female sex workers (FSW) infected with human immunodeficiency virus (HIV) and sexually transmitted disease (STD) in the first compulsory drug addiction treatment center in Yunnan province in 2012 to provide basis for prevention and treatment of AIDS and STD in this population . Methods The venous blood samples were collected for the detection of HIV and vaginal discharge. Fluorescent quantitative PCR was used to detect the major pathogens of STD: CT, UU, NG, HSV- Ⅱ), Papillomavirus 6,11 (HPV 6,11), Papillomavirus high-risk type (HPV HR). Results Among the 143 subjects tested, 6 cases were detected with HIV infection and the infection rate was 4.19%. The detection of STD pathogens was CT16 (11.19%), UU 86 (60.14%), NG 4 (2.80%), HSV- There were 32 cases (22.38%) of type Ⅱ, 7 cases (4.89%) of HPV, 11 cases of HPV (35.66%), and 196 cases of STD were detected. Only 6 cases were not detected. 66 cases (46.15%) were infected with a single pathogen and 71 (49.65%) with mixed pathogens. Conclusions Among HIV-infected female sex workers, the infection of HIV and STD can not be neglected. The two promote and interact with each other. Health education should be strengthened for such people and effective interventions should be taken to control the spread of STD and HIV.