论文部分内容阅读
溶菌酶(Lysozyme)在局部组织和器官的防御中起主要作用。作者观察了31例喉癌(角化型鳞癌18例,非角化型10例,低分化型2例,乳头状瘤癌变1例。病期:Ⅱ9例,Ⅲ_a 15例,Ⅲ_b6例,Ⅳ1例),并检查了癌灶及其周围组织(距癌灶0.5,1.0及1.5 cm)的溶菌酶含量。检测结果:癌灶内的含量亦低。邻近肿瘤边缘外观正常的组织,溶菌酶含量降低到6.2±0.5μg/mg蛋白,组织学检查其中17例有癌瘤结构。距癌灶1～1.5 cm的含量为11.4±0.6μg/mg蛋白(属正常值),此处在镜检下均未见癌细胞。按在内生型及放疗后再手术的病例,肉眼很难区分肿瘤和健康组织界限。因此,作者认为喉癌手术应
Lysozyme plays a major role in the defense of local tissues and organs. The authors observed 31 cases of laryngeal carcinoma (18 cases of keratinizing squamous cell carcinoma, 10 cases of non-keratinized, 2 cases of poorly differentiated, 1 case of papilloma carcinoma. Period of disease: II 9 cases, III a a 15 cases, III b 6 cases, IV 1 Example) and examined the lysozyme content of the foci and their surrounding tissues (0.5, 1.0 and 1.5 cm from the foci). Test results: The content in the foci is also low. In the tissue with normal appearance near the edge of the tumor, the lysozyme content was reduced to 6.2±0.5 μg/mg protein, and histological examination showed that 17 cases had a cancerous structure. The content of tumor from 1 to 1.5 cm was 11.4±0.6 μg/mg protein (normal value). There was no cancerous cell under microscope examination. According to endogenous and radiotherapy reoperation cases, it is difficult for the naked eye to distinguish between tumor and healthy tissue boundaries. Therefore, the author believes that laryngeal cancer surgery should