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用一组雌激素相关标志对54例女性乳腺癌进行回顾性研究。患者平均47.9岁,5年生存率为81.5%。癌肿长径平均3.4cm,浸润性导管癌49例,Ⅲ级36例。肿瘤大小、组织学类型、分级与预后关系不明显。ER阳性率55.6%,PR阳性率389%,与组织蛋白酶D有较好相关性。组织蛋白酶D在癌细胞的阳性年为278%,间质巨噬细胞阳性率为100%,与ER、PR关系较密切,并与预后相关。
A retrospective study of 54 women with breast cancer was performed using a set of estrogen-related markers. The average patient age was 47.9 years and the 5-year survival rate was 81.5%. The average diameter of the cancer was 3.4cm. There were 49 cases of invasive ductal carcinoma and 36 cases of grade III. There was no significant relationship between tumor size, histological type, grade, and prognosis. The positive rate of ER was 55.6%, and the positive rate of PR was 389%. It had a good correlation with cathepsin D. Cathepsin D had a positive rate of 278% in cancer cells, and the positive rate of interstitial macrophages was 100%. It was closely related to ER and PR, and related to prognosis.