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儿童期肥胖易导致成年高血压和糖尿病。研究者已发现儿童期肥胖与青春期早期胰岛素抵抗增加相关。该研究旨在探讨这些肥胖轨迹与儿童期血压发展的关系。方法:在西澳大利亚怀孕队列后代从0到14岁时,采用系列人体测量,通过半参数混合模型描绘出7种肥胖轨迹。Logistic回归分析17岁时这些肥胖轨迹与高血压、正常高值血压发病率的相关性。线性混
Childhood obesity easily lead to adult hypertension and diabetes. Researchers have found that childhood obesity is associated with an increase in early adolescent insulin resistance. The aim of this study was to investigate the relationship between these obesity trajectories and the development of childhood blood pressure. METHODS: Seventy obese loci were depicted by a series of anthropometric measurements from semi-parametric mixed models at the age of 0 to 14 years in the offspring of the pregnant cohort in Western Australia. Logistic regression analysis of the correlation between these obesity trajectories and the prevalence of hypertension and normal high blood pressure at 17 years of age. Linear mixed