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前列腺素是一种生物活性酸基脂类。近期研究认为它与抗原抗体相互作用后炎症反应有关。作者已经从猪鼻粘膜分离得到前列腺素E 系列。本研究旨在比较前列腺素和肾上腺素对鼻粘膜血管效应之不同,以期发现两种效应的相关性。同时研究PGI_2 和PGD_2 对鼻血管的作用。选用麻醉状态猪,封闭鼻咽腔,从前鼻孔置管连接容积描记器记录鼻腔内压力变化,并从股动脉插管测动脉血压变化。从舌动脉逆行插管,
Prostaglandins are bioactive acid-based lipids. Recent studies suggest that it is related to the inflammatory response after antigen-antibody interaction. The authors have isolated prostaglandin E series from porcine nasal mucosa. The purpose of this study was to compare the effects of prostaglandins and epinephrine on nasal mucosal vascular effects in order to find the correlation between the two effects. The effect of PGI_2 and PGD_2 on nasal blood vessels was also studied. Selection of anesthetized pigs, the closure of the nasopharyngeal cavity, past the nasal cannula connection plethysmograph to record changes in nasal pressure, and measured from the femoral artery arterial blood pressure changes. Reversal intubation from the lingual artery,