为评价CyFRA21-1对肺癌的诊断价值。采用免疫量度分析法测定肥例肺癌患者和42例肺良性疾病者及30例健康人血清中的CyFRA21-1和鳞癌相关抗原（SCC－Ag）含量。CyFRA21－1和SCC－Ag的临界值分别为3．3μg／L和1．5μg／L。特异性均为92．5％时，对肺癌诊断的敏感性CyFRA21－1为53．91％，SCC－Ag为23．17％，鳞癌分别为63．80％和39．33％。说明CyFRA21－1对NSCLC尤其是鳞癌的诊断有一定意义，其性能明显优于SCC－Ag。 To evaluate the diagnostic value of CyFRA21-1 for lung cancer. The serum CyFRA21-1 and squamous-cell carcinoma-associated antigen (SCC-Ag) levels in the lungs of patients with lung cancer, 42 patients with benign lung diseases, and 30 healthy individuals were measured by immunoassay. The critical values ​​of CyFRA21-1 and SCC-Ag were 3.3 μg/L and 1.5 μg/L, respectively. When the specificity was 92.5%, the sensitivity of the diagnosis of lung cancer was 53.91% for CyFRA21-1, 23.17% for SCC-Ag, and 63.80% and 39.33% for squamous cell carcinoma, respectively. This shows that CyFRA21-1 has certain significance for the diagnosis of NSCLC, especially squamous cell carcinoma, and its performance is obviously better than that of SCC-Ag.