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1975年O’Brein 首先提出“日光性肉芽肿”,并描述此为经常曝晒阳光皮肤处的环状病灶。在显微镜检时,可发现弹性纤维被多核巨细胞与组织球所清除。日光性肉芽肿除了在皮肤被发现外,外眼结膜上之病便亦被提及(1983,Proia)。皮肤型日光性肉芽肿有些同义词,包括“非典型环状类脂肪渐近性坏死症”,‘Miescher’s肉芽肿’,与“环状弹性纤维分解性巨细胞肉芽肿”等。临床上,眼结膜型日光性肉芽肿,眼结膜黄斑与眼结膜翼状赘片相近,其主要的病理变化都是日光弹性纤维增加。而皮肤型日光性肉芽肿则与环状肉芽肿相近,眼结膜型与皮肤型日光性肉芽肿都有明显的三个区域明显变化:
O’Brein first proposed “solar-granuloma” in 1975 and described it as a ring-shaped lesion at sun-exposed skin. At microscopic examination, elastic fibers were found to be cleared by multinucleated giant cells and histospheres. In addition to being found on the skin, solar granuloma is also mentioned on the outer conjunctiva (1983, Proia). Dermatoglyphs are synonymous with “atypical ascorbic asystosis,” “Miescher’s granuloma,” and “ring-like elastolytic giant cell granuloma.” Clinically, conjunctival solar granuloma, conjunctival macula and conjunctival pterygium are similar, the main pathological changes are increased daylight elastic fibers. The skin-type solar granuloma is similar to the ring-shaped granuloma, conjunctival and skin-type daylight granulomas have significant changes in the three regions: