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目的分析腔隙性脑梗死患者血浆同型半胱氨酸(Hcy)水平与脑动脉搏动指数(PI)的关系。方法 79例腔隙性脑梗死患者,根据Hcy检测结果将患者分为血浆Hcy正常组12例,轻度升高组44例,中重度升高组23例。对比分析三组患者的PI值。结果血浆Hcy正常组患者平均PI为(0.84±0.23),轻度升高组为(0.95±0.28),中重度升高组为(1.13±0.32),血浆Hcy中重度升高组PI值>血浆Hcy轻度升高组>血浆Hcy正常组,差异均具有统计学意义(P<0.05)。相关性分析结果显示患者血浆Hcy水平与PI值呈正相关(r=0.318,P=0.005<0.05)。结论腔隙性脑梗死患者血浆Hcy水平与PI存在显著关系,血浆Hcy水平的升高可能是脑小血管性卒中的危险因素。
Objective To analyze the relationship between plasma homocysteine (Hcy) level and cerebral arterial pulse rate (PI) in patients with lacunar infarction. Methods A total of 79 patients with lacunar infarction were divided into Hcy normal plasma group (n = 12), moderate hypothyroidism group (n = 44) and moderate to severe hypothyroidism group (n = 23) according to the Hcy test results. Comparative analysis of three groups of patients PI value. Results The average PI of normal Hcy group was (0.84 ± 0.23), slightly elevated group (0.95 ± 0.28), moderate and severe elevated group (1.13 ± 0.32) Hcy mild increase group> plasma Hcy normal group, the difference was statistically significant (P <0.05). Correlation analysis showed that plasma Hcy level was positively correlated with PI (r = 0.318, P = 0.005 <0.05). Conclusion The plasma Hcy levels in patients with lacunar infarction have a significant relationship with PI. Elevated plasma levels of Hcy may be the risk factors for cerebral vascular stroke.