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目的分析大连大学附属新华医院2012-2015年临床分离的常见细菌种类、分布及耐药情况。方法对培养鉴定的细菌种类和药敏情况进行分析。结果细菌培养标本阳性检出率平均为34.25%,表现逐年上升趋势;细菌标本来源主要以痰标本为主,平均占总标本量的52.75%,其次为尿液标本和血液标本,分泌物标本相对较少,但有上升趋势;四年中细菌分离情况显示常见细菌有6种,分别为大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌、鲍曼不动杆菌、凝固酶阴性葡萄球菌和金黄色葡萄球菌;耐药结果显示头孢哌酮/舒巴坦对上述前4种细菌的耐药率均小于10%,其中耐药性最高的为鲍曼不动杆菌。结论合理应用抗生素,可提高治疗效果,减少医院感染的发生。
Objective To analyze the common bacterial species, distribution and drug resistance in clinical isolation of Xinhua Hospital Affiliated to Dalian University from 2012 to 2015. Methods Bacterial species and susceptibility were analyzed. Results The positive rate of bacterial culture samples was 34.25% on average, showing an upward trend year by year. The main source of bacterial samples were sputum samples, accounting for 52.75% of the total samples, followed by urine samples and blood samples, But there is an upward trend. In the past four years, bacterial isolation showed that six kinds of common bacteria were Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, coagulase-negative grape Cocci and Staphylococcus aureus. The resistant rate of cefoperazone / sulbactam to these four bacteria was less than 10%, and Acinetobacter baumannii was the most resistant. Conclusion The rational use of antibiotics can improve the therapeutic effect and reduce the occurrence of nosocomial infections.