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恶性脑膜瘤与浸润性脑膜瘤的组织学改变和生物学行为有一定程度的相似性,为提高其诊断水平,作者对90例恶性脑膜瘤和18例浸润性脑膜瘤进行了对比研究。结果表明:在脑膜瘤组织变化的基础上出现肿瘤细胞丰富密集,异型性增大,瘤巨细胞,10个高倍视野下核分裂数在6个以上,甚至出现病理性核分裂,瘤组织灶性或点状坏死,囊性变和出血时可诊断为恶性脑膜瘤,如再出现浸润性生长、复发或转移,则更可诊断为恶性脑膜瘤。在良性脑膜瘤病变的基础上出现浸润性生长则诊断为浸润性脑膜瘤。
Malignant meningioma and invasive meningioma histological changes and biological behavior have a certain degree of similarity, in order to improve their diagnostic level, the author of 90 cases of malignant meningioma and 18 cases of invasive meningioma compared. The results showed that on the basis of the changes of meningioma tissue, the tumor cells were dense and atypia, the number of tumorous giant cells, the number of fission in more than 6 fields were more than 6, even pathological mitosis, tumor tissue or point Necrotic, cystic and hemorrhagic bleeding can be diagnosed as malignant meningiomas, such as recurrence of invasive growth, recurrence or metastasis, the more can be diagnosed as malignant meningiomas. On the basis of benign meningioma, invasive growth is diagnosed as invasive meningioma.