目的　比较两种方案治疗肝硬化食管胃底静脉曲张破裂出血的疗效。方法　对 4 2例肝硬化食管胃底静脉曲张破裂出血病人用胃复安联合垂体后叶素和硝酸甘油治疗 ;另 4 1例采用垂体后叶素 +硝酸甘油治疗。结果　 2 4h内止血率 92 .86% ( 39/ 4 2 ) ,平均止血时间 ( 5.8± 4 .8)h ,其效果明显优于垂体后叶素 +硝酸甘油的治疗效果 ,P <0 .0 5。结论　胃复安联合垂体后叶素、硝酸甘油治疗肝硬化食管胃底静脉曲张破裂出血 ,近期疗效好 ,安全可靠 ,值得临床推广。 Objective To compare the efficacy of two regimens in the treatment of patients with esophageal and gastric variceal bleeding due to cirrhosis. Methods Forty-two patients with esophageal-gastric variceal bleeding were treated with metoclopramide combined with pituitary vasopressin and nitroglycerin. The other 4 cases were treated with pituitrin and nitroglycerin. Results The rate of hemostasis within 24 h was 92.86% (39/42), and the mean hemostasis time was 5.8 ± 4.8 h, which was significantly better than that of pituitrin and nitroglycerin (P <0. 0) 5. Conclusion The combination of metoclopramide and pituitrin, nitroglycerin in the treatment of cirrhosis and esophagogastric variceal bleeding, the recent good effect, safe and reliable, worthy of clinical promotion.