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目的:比较多索茶碱与氨茶碱用于治疗支气管哮喘患者止喘的临床疗效。方法:选取2012年12月1日—2015年12月1日间诊治的支气管哮喘患者120例,将其分为干预组60例和对照组60例;干预组患者给予多索茶碱治疗,对照组患者给予氨茶碱治疗,比较两组患者临床治疗后总有效率、肺功能各指标改善情况和不良反应的发生率。结果:干预组患者治疗后的总有效率为98.33%高于对照组为80.00%(P<0.05),肺功能各指标改善状况显著优于对照组(P<0.05),用药期间不良反应的发生率优于对照组(P<0.05)。结论:临床观察结果发现,采用多索茶碱治疗支气管哮喘患者,不仅能够提高治疗的总有效率,而且能够减少不良反应的发生率,其临床疗效优于氨茶碱的疗效。
Objective: To compare the clinical efficacy of doxofylline and aminophylline in the treatment of asthma in patients with bronchial asthma. Methods: 120 patients with bronchial asthma who were diagnosed and treated between Dec. 1, 2012 and Dec. 1, 2015 were divided into intervention group (60 cases) and control group (60 cases). Patients in intervention group were treated with doxofylline Patients in group A were treated with aminophylline. The total effective rate, the improvement of pulmonary function indexes and the incidence of adverse reactions in both groups were compared. Results: After treatment, the total effective rate of the intervention group was 98.33%, which was significantly higher than that of the control group (80.00%, P <0.05). The improvement of various indexes of lung function was significantly better than that of the control group (P <0.05). The incidence of adverse reactions Rate was better than the control group (P <0.05). Conclusion: The clinical observation shows that the use of doxofylline in patients with bronchial asthma, not only can improve the total effective rate of treatment, but also reduce the incidence of adverse reactions, and its clinical efficacy is superior to the efficacy of aminophylline.