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目的:探讨低分子肝素联合清热凉血方保留灌肠对慢性非特异性溃疡性结肠炎的治疗作用。方法:82例患者随机分为两组,分别为低分子肝素联合清热凉血方灌肠组(治疗组n=41)与单纯清热凉血方灌肠组(对照组n=41)。治疗组用清热凉血方100 mL.d-1,联合低分子肝素5 000 u,bid治疗,对照组用清热凉血方灌肠,100 mL.d-1。治疗2周后观察疗效。结果:治疗组和对照组的近期治愈率差异有统计学意义(P<0.05)。结论:低分子肝素联合清热凉血方是治疗慢性非特异性溃疡结肠炎的有效方法,有推广价值。
Objective: To investigate the therapeutic effect of low molecular weight heparin combined with Qingre Liangxue prescription enema on chronic nonspecific ulcerative colitis. Methods: 82 patients were randomly divided into two groups: low molecular weight heparin combined with Qingre Liangxue enema group (n = 41 in treatment group) and Qingre Liangxue enema group (n = 41 in control group). The treatment group with Qingre Liangxue 100 mL.d-1, combined with low molecular weight heparin 5000 u, bid treatment, the control group with heat and cooling enema, 100 mL.d-1. After 2 weeks of treatment, the curative effect was observed. Results: There was significant difference in the recent cure rate between the treatment group and the control group (P <0.05). Conclusion: Low molecular weight heparin combined with Qingre Liangxue prescription is an effective method for the treatment of chronic nonspecific ulcer colitis, which has the promotion value.