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目的提高对神经梅毒的认识。方法对3例以癫为临床首发症状并确诊为神经梅毒的临床资料进行回顾性分析。结果3例患者均以癫为临床首发症状,血清、脑脊液的快速血浆反应素试验(RPR试验)和梅毒螺旋体明胶凝集试验(TPPA试验)均阳性,脑脊液的蛋白含量均异常,细胞学检查1例异常,2例患者EEG示样放电,经大剂量青霉素等治疗后癫症状消失。结论对于成年人初次发作的癫应考虑排除神经梅毒的可能。
Objective To improve the understanding of neurosyphilis. Methods The clinical data of 3 cases with epilepsy as the first clinical symptom and diagnosed as neurosyphilis were retrospectively analyzed. Results Epilepsy was the first clinical symptom in all 3 patients. The serum and cerebrospinal fluid were both positive by RPR and TPPA, and the protein content of cerebrospinal fluid was abnormal. Cytology 1 Cases of abnormalities, 2 patients showed EEG like discharge, after treatment with high-dose penicillin epileptic symptoms disappear. Conclusion For the first episode of adult epilepsy should consider the possibility of excluding neurosyphilis.